Business idea · Physical-Services

Fecal Microbiota Startups

Fecal Microbiota Startups is a startup that focuses on fecal microbiota transplants (FMT) for health benefits, including improved gut health and possibly enhancing athletic performance. It was pitched on My First Million in the episode "We found the weirdest ways to make $1M, $1B, and $5B" (aired June 13, 2025).

At a glance

Fecal Microbiota Startups at a glance
PodcastMy First Million
Hosted bySam Parr and Shaan Puri
EpisodeWe found the weirdest ways to make $1M, $1B, and $5B
AiredJune 13, 2025
CategoryPhysical-Services
Real companies on the episodeBrazilian Butt Lift (BBL), Zico Coconut Water, Torque Out, Tushy, Hostage Tape, Dude Wipes

The problem it solves

The startup addresses gut health issues and offers a novel approach to improving conditions such as Crohn's disease, colitis, and potentially even enhancing athletic performance through microbiome optimization.

How it makes money

The business could operate on a subscription model for ongoing treatments or consultations, along with partnerships with health professionals for referrals.

Skills you need

Skills needed include medical knowledge, research and development in microbiome science, marketing, and business development.

The market, and why this works now

The FDA's 2013 guidance on fecal microbiota transplants has paved the way for startups in this sector, allowing for regulated clinical applications. A viable first-revenue move involves targeting health-focused communities on platforms like Reddit, specifically subreddits dedicated to gut health and fitness, where potential customers actively seek solutions. However, the startup will face significant regulatory friction and capital requirements, as navigating compliance for medical treatments can be costly and time-consuming, potentially delaying market entry.

Our analysis, written after the episode. Not a quote from the show.

Real companies discussed on this episode

  • Brazilian Butt Lift (BBL)

    A cosmetic surgery procedure that transfers fat from the belly to the buttocks for enhancement.

  • Zico Coconut Water

    A brand of coconut water that was popular for its natural hydration benefits.

  • Torque Out

    A fitness class that teaches women how to twerk, capitalizing on the trend of twerking.

  • Tushy

    A company that provides bidet attachments for toilets.

  • Hostage Tape

    A product designed to help users breathe better during sleep by taping their mouths shut.

  • Dude Wipes

    A brand specializing in flushable wet wipes designed for men.

Where this idea came from

Podcast: My First Million, hosted by Sam Parr and Shaan Puri

Episode: We found the weirdest ways to make $1M, $1B, and $5B

Aired:

Summarized from the episode transcript. The show does not say which speaker raised each idea, so we credit the show, not a person.

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What to do next

  1. Listen to the episode. "We found the weirdest ways to make $1M, $1B, and $5B" on My First Million
  2. Study a real company from the episode: Brazilian Butt Lift (BBL)
  3. Find an idea that fits your budget, hours and skills
  4. Compare it with a similar idea: Christmas Light Installation

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